ToolsHistone methylation 연구에 필요한 제품을 확인해 보세요

2024-02-16
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Histone methylation

Epigenetics에서 가장 대표적인 분야인 Histone methylation 관련 연구를 위한 Abcam의 다양한 제품을 만나보세요!


Histone methyltransferase activity assay

Histone modificationCat no.Product name
Histone H3 (K4)ab113452Histone H3 (K4) Methyltransferase Activity Quantification Assay Kit
Histone H3 (K9)ab113453Histone H3 (K9) Methyltransferase Activity Quantification Assay Kit
Histone H3 (K27)ab113454Histone H3 (K27) Methyltransferase Activity Quantification Assay Kit


Histone demethylase activity assay

TaragetCat no.Product name
H3K4 demethylationab113455Histone Demethylase (H3K4) Activity Quantification Assay Kit
H3K4me2/me3
(KDM1/LSD1)
ab113459KDM1/LSD1 Activity Quantification Assay Kit (Colorimetric)
ab113460KDM1/LSD1 Activity Quantification Assay Kit (Fluorometric)
H3K4me2/me3
(KDM5/JARID)
ab113463KDM5/JARID Activity Quantification Assay Kit (Colorimetric)
ab113464KDM5/JARID Activity Quantification Assay Kit (Fluorometric)
H3K9me3
(KDM4A/JHDM3A/JMJD2A, KDM4B/JMJD2B, KDM4C/GASC1/JMJD2C, KDM4D/JMJD2D)
ab113461KDM4/JMJD2 Activity Quantification Assay Kit (Colorimetric)
ab113462KDM4/JMJD2 Activity Quantification Assay Kit (Fluorometric)
H3K27me3
(KDM6A/UTX, KDM6B/JMJD3)
ab156910KDM6A/ KDM6B Activity Quantification Assay Kit (Colorimetric)
ab156911KDM6A/KDM6B Activity Quantification Assay Kit (Fluorometric)


Histone demethylase inhibitor assay

TargetCat no.Product name
H3K4me2/me3 (KDM1/LSD1)ab113456Histone Demethylase KDM1/LSD1 Inhibitor Assay Kit


Histone methyltransferase inhibitor

TargetCat no.InhibitorNotes
EZH2
(H3K27me3)
ab269816GSK126Potent and selective inhibitor
ab269819GSK503
ab218610GSK343
ab269817EI1
ab269818CPI-169
ab146152UNC1999
ab1422153-deazaneplanocin A
Also inhibit trimethylation of H4K20 in vitro
ab1456283-deazaneplanocin A hydrochloride (DZNep)
KMT1A/SUV39
(H3K9me3)
ab144534ChaetocinAlso inhibit other K9-specific HMTs
SET domain-containing HMTsab144518SinefunginAnalogue of S-adenosyl-methionine (SAM)
EHMT1/GLP, EHMT2/G9A
(H3K9me2/3)
ab142157UNC0638Also selective against SET7/9 (H3K4 HMTase), SET8 (H4K20 HMTase), PRMT3, and SUV39H2
EHMT2/G9a
(H3K9me2/3)
ab141407BIX-01294Selective inhibitor
SETD7
(H3K4me2)
ab223601PFI-2Potent and selective inhibitor
DOT1L
(H3K79)
ab145525Compound 55


Histone demethylase inhibitor

TargetCat no.InhibitorNotes
KDM6A/UTX, KDM6B/JMJD3
(H3K27me3)
ab144396GSK-J1Also inhibit KDM5B and KDM5C
ab144398GSK-J2GSK-J1 isomer for use as a less-active control
ab144395GSK-J4Ester pro-drug of GSK-J1
ab144397GSK-J5Ester pro-drug of GSK-J2
KDM2/7 subfamily
(H3K9me3)
ab144621DaminozideHighly selective over other subfamily members (KDM3/4/5/6) and other 2-oxoglutarate oxygenase
JMJC-domain containing enzymeab144394IOX1Inhibits most 2-oxoglutarate oxygenase
ab144566Methylstat
LSD1ab254459SP-2509Potent, selective and reversible inhibitor


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