Abcam코로나바이러스(SARS-CoV-2, 코로나19) 연구와 관련된 제품 정보

코로나바이러스(SARS-CoV-2, 코로나19) 연구와 관련된 제품 정보


Background to coronaviruses

왕관 모양의 코로나바이러스는 1960년대에 처음으로 밝혀졌고, 호흡기 증상과 관련이 있습니다. 메르스(MERS-CoV), 사스(SARS-CoV)는 사람에게 감염되어 폐렴, 중증급성호흡기증후군을 일으켜 사망에 이르게도 합니다. 2019-nCoV(SARS-CoV-2, 국내 명칭 코로나19)는 가장 최근에 밝혀진 코로나바이러스 변종 입니다.

(이미지 출처 : Wikipedia)


Coronavirus research

중국 과학자들이 SARS-CoV와 구분되는 group 2B CoV신종 코로나바이러스를 밝혔고, genome sequencing을 통해 코로나19가 SARS-CoV와 79.5%, 박쥐의 코로나바이러스와 96%가 일치하는 것을 입증하였습니다.

숙주 세포에 접근하기 위해서 코로나바이러스는 spike protein을 통해 숙주 세포의 특정 receptor에 부착합니다. 때문에 SARS-CoV는 숙주 세포의 ACE-2(angiotensin converting enzyme II) receptor를, MERS-CoV는 CD26(DPP4)를 각각 이용합니다. 최근 연구는 코로나19 역시 SARS-CoV 처럼 ACE-2 를 이용할 수 있는 것으로 결과를 보여주고 있습니다.

현재 코로나19(SARS-CoV-2) 치료를 위한 백신이나 치료제가 없는 상황으로, 과학자들은 잠재적인 백신과 코로나19(SARS-CoV-2) 혹은 바이러스 복제를 위해 필요한 숙주 세포 구성(receptor)을 타겟으로 하는 치료제를 찾고 있습니다.


Products to support coronavirus research

Abcam은 코로나19(SARS-CoV-2)를 포함한 감염병 연구에 박차를 가하고 그에 대한 이해를 위한 다양한 툴을 제공하고 있습니다. 아래에 정리 된 human coronavirus 관련 항체와 단백질, cytokine 검출 관련 제품 정보를 통해 관련 제품을 빠르게 확인하세요.


Homology comparison of COVID-19 proteins and the corresponding SARS proteins

ProteinsSARS Uniprot IDHomology to COVID-19
EnvelopeP5963792%
MembraneP5959690%
NucleocapsidP5959590%
SpikeP5959474%



Antibodies specific for Human Coronaviruses   

Product
ab273073New Recombinant Anti-SARS-CoV-2 Spike Glycoprotein S1 antibody [CR3022]Neutralising, ELISASARS-CoV, SARS-CoV-2
ab272852NewRecombinant Anti-SARS-CoV-2 nucleocapsid protein antibody [1A6] - Chimeric WB, ELISAHuman coronavirus
ab273168NewRecombinant Anti-SARS-CoV-2 nucleocapsid protein antibody [1A6] - Chimeric (HRP)
ELISAHuman coronavirus
ab273167NewAnti-SARS-CoV-2 nucleocapsid protein antibody
IHC, WBHuman coronavirus
ab272504NewAnti-SARS-CoV-2 spike glycoprotein antibody - Coronavirus ELISA, WBPredict : Human coronavirus
ab273074NewRecombinant Anti-SARS-CoV-2 Spike Glycoprotein S1 antibody [CR3022] - ChimericNeutralising, ELISASARS-CoV, SARS-CoV-2
ab272854NewRecombinant Anti-SARS-CoV-2 spike glycoprotein antibody [H6] - ChimericELISA Human coronavirus
ab273169NewRecombinant Anti-SARS-CoV-2 spike glycoprotein antibody [H6] - Chimeric (HRP)
ELISAHuman coronavirus
ab272503NewAnti-SARS-CoV-2 envelope protein antibody - Coronavirus ELISA Predict : Human coronavirus
ab272420NewAnti-SARS spike glycoprotein antibody [3A2] - CoronavirusWB, ICC/IFHuman coronavirus, SARS-CoV
ab273433NewAnti-SARS spike glycoprotein antibody [1A9]
ELISA, Flow Cyt, ICC/IF, IP, sELISA, WB
SARS-CoV, SARS-CoV-2
ab252690Anti-SARS spike glycoprotein antibody- C-terminalELISASARS spike glycoprotein
ab252691Anti-SARS spike glycoprotein antibody- N-terminalELISASARS spike glycoprotein 
ab273436Anti-SARS spike glycoprotein S1 antibody [7G12]
IPWB
SARS-CoV
ab273434NewAnti-SARS Nucleoprotein antibody [6H3]
ELISA, ICC/IF, IP, sELISA, WB
SARS-CoV, SARS-CoV-2
ab31951Anti-SARS E2 antibody [4A6C9]ELISA, WBHuman coronavirus
ab22055Anti-SARS E antibodyWBSARS E - Coronavirus


* 관련된 전체 제품 리스트는 여기(클릭)서 확인 하세요!


Human Coronaviruses  Proteins and Peptides

Cat noProductApplication Active
ab272107Recombinant Human coronavirus SARS CoV-2 Nucleoprotein (His tag)SDS-PAGENo
ab273065NewRecombinant human coronavirus SARS-CoV-2 Spike Glycoprotein RBD (Active)  ELISA, Flow Cyt, SDS-PAGEYes
ab272105Recombinant Human coronavirus SARS-CoV-2 Spike Glycoprotein S1 (Fc Chimera)  SDS-PAGENo
ab273068NewRecombinant human coronavirus SARS-CoV-2 Spike Glycoprotein S1 (Active)FuncS, SDS-PAGEYes
ab272106Recombinant Human coronavirus SARS-CoV-2 Spike Glycoprotein S2 (Fc Chimera)  SDS-PAGENo
ab273066NewRecombinant Human coronavirus SARS-CoV-2 Spike Glycoprotein RBD (Tagged)  SDS-PAGENo
ab273067NewRecombinant Human coronavirus SARS-CoV-2 Spike Glycoprotein S1 (Tagged)  SDS-PAGENo
ab270828Canine coronavirus (photochemically inactivated)  ELISA No
ab48951Recombinant SARS M protein (Coronavirus)  ELISA, WBNo
ab270842Recombinant Human coronavirus SARS Nucleocapsid Protein (Tagged)  ELISA, SDS-PAGE, WBNo
ab270839Recombinant Human coronavirus SARS spike glycoprotein (Tagged)  ELISA, SDS-PAGE, WBNo
ab270833Recombinant Human coronavirus SARS CoV Envelope protein  ELISA, SDS-PAGE, WBNo
ab272108Recombinant Human coronavirus SARS Nucleoprotein (His tag)  SDS-PAGENo 
ab270825Recombinant Human coronavirus SARS NucleoproteinELISA, SDS-PAGE, WBNo
ab273063NewHuman coronavirus SARS-CoV-2 spike glycoprotein peptide
BL
ab273064NewHuman coronavirus SARS-CoV-2 envelope protein peptide
BL

 관련된 전체 제품 리스트는 여기(클릭)서 확인 하세요!


ELISA kits for COVID-19 proteins

Cat no.ProductAssay typeDetection rangeSample type
ab274341
NewCOVID-19 N-Protein ELISA Kit
Sandwich (quantitative)
0.069 ng/ml - 50 ng/ml
Cell culture supernatant, Serum
ab274342
NewCOVID-19 Spike Protein ELISA Kit
Sandwich (quantitative)
2.744 ng/ml - 2000 ng/ml
Cell culture supernatant, Serum


ACE2 and TMPRSS2 antibodies and ELISA kits 

Cat no.ProductSpeciesApplication
ab235649Human ACE2 ELISA KitHumanELISA
ab213843Mouse ACE2 ELISA KitMouseELISA
ab244135Human ACE2 Antibody Pair - BSA and Azide freeHumanELISA
ab108252Recombinant Anti-ACE2 antibody [EPR4435(2)]Mouse, Rat, HumanIHC-P, IP, WB
ab239924Recombinant Anti-ACE2 antibody [EPR4435(2)] - BSA and Azide freeMouse, Rat, HumanIHC-P, IP, WB
ab15348Anti-ACE2 antibodyCat, Human, Ferret, Macaque monkey, BatIHC-Fr, ICC/IF, WB, IHC-P
ab151852Recombinant Human ACE2 proteinHumanSDS-PAGE, HPLC
ab108209Anti-ACE2 antibody [EPR4436]HumanWB, IP, IHC-P
ab109131Recombinant Anti-TMPRSS2 antibody [EPR3862]Mouse, Rat, HumanICC/IF, WB, IHC-P
ab92323Recombinant Anti-TMPRSS2 antibody [EPR3861]Mouse, Rat, Human, Cynomolgus monkey, Rhesus monkey, Common marmosetWB, IHC-P

* 관련된 전체 제품 리스트는 여기(클릭)서 확인 하세요!


Cytokine detection products 

Cat no.ProductSpeciesApplication
ab9722Anti-IL-1 beta antibodyMouse, Rat, HumanWB, ELISA, Neutralising, IHC, ICC/IF
ab174444Human IL-2 ELISA KitHumanELISA
ab178013Human IL-6 ELISA KitHumanELISA
ab9324Anti-IL-6 antibodyRat, HumanICC/IF, IHC, Neut, sELISA, WB
ab79056Anti-IL-17 antibodyMouse, Dog, HumanELISA, ICC/IF, IHC-Fr, IHC-P, WB
ab236895Human IFN gamma High Sensitivity ELISA KitHumanELISA
ab9657Anti-Interferon gamma antibodyMouse, Human, Macaque monkeyICC/IF, IHC-P, Neut, sELISA, WB
ab9807Anti-IP10 antibodyHumanELISA, IHC-Fr, IHC-P, Neut, WB
ab181421Human TNF alpha ELISA KitHumanELISA
ab6671Anti-TNF alpha antibodyHuman, Cynomolgus monkeyELISA, ICC/IF, IHC-P, WB
ab222510Human VEGF ELISA KitHumanELISA
ab1316Anti-VEGFA antibody [VG-1]Mouse, Rat, Rabbit, Dog, HumanELISA, ICC, ICC/IF, IHC, IP, WB
ab52917Anti-VEGFA antibody [EP1176Y] - C-terminalMouse, HumanFlow Cyt, ICC/IF, IHC-P, IP, WB

* 관련된 전체 제품 리스트는 여기(클릭)서 확인 하세요!


Rapid SARS-CoV-2 lateral flow assays 

Cat no.ProductDetectsSample typeTime to results
ab272243Novel Coronavirus IgG Antibody Detection KitCoronavirus N-Protein IgG antibodiesHuman serum, plasma, whole blood8-10 min
ab272244Novel Coronavirus IgM Antibody Detection KitCoronavirus N-protein IgM antibodiesHuman serum, plasma, whole blood8-10 min



For latest information on the outbreak, please visit the World Health Organization (WHO) website

* 해당 내용은 abcam 홈페이지의 원문을 옮겨왔습니다.


* 학술 문의    Tel.  031-728-3234     E-mail.  technical@dawinbio.com


 




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