TLR & NLR Signaling Pathways : Invivogen 제품 소개

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TLR Ligand

Product	Specificity	Origin/Description	Endotoxin level	Working conc.	Qty	Cat no.
Pam3CSK4	TLR 1/2 agonist	Synthetic triacylated lipopeptide (LP)	EndoFit™	1 - 300 ng/ml	1 mg	tlrl-pms
FSL-1	TLR2/6 agonist	Synthetic triacylated lipopeptide (LP)	EndoFit™	1 - 100 ng/ml	100 μg	tlrl-fsl
Poly(I:C) (HMW)	TLR3 agonist	Polyinosinic-polycytidylic acid Long synthetic analog of dsRNA	EndoFit™	30 ng- 10 μg/ml	10 mg 50 mg	tlrl-pic tlrl-pic-5
Poly(I:C) (LMW)	TLR3 agonist	Polyinosinic-polycytidylic acid Short synthetic analog of dsRNA	EndoFit™	30 ng- 10 μg/ml	25 mg 250 mg	tlrl-picw tlrl-picw-250
LPS-EB	TLR2/4 agonist	Standard LPS, E. coli 0111:B4	> 1 x 10⁶ EU/mg	10 ng - 10 μg/ml	5 mg	tlrl-eblps
LPS-PG	TLR2/4 agonist	Lipopolysaccharide from P. gingivalis	> 1 x 10⁵ EU/mg	TLR4: 100 ng - 10 μg/ml TLR2: 10 ng/ml - 10 mg/ml	1 mg	tlrl-pglps
FLA-ST	TLR5 agonist	Standard flagellin from S. typhimurium	1 - 10 EU/μg	10 ng - 10 μg/ml	100 µg	tlrl-stfla
R848 (Resiquimod)	TLR7/8 agonist	Imidazoquinoline compound	EndoFit™	10 ng - 10 μg/ml	500 μg 5 mg	tlrl-r848 tlrl-r848-5
TL8-506	TLR8 agonist	Benzoazepine analog	EndoFit™	10 - 100 ng/ml	500 μg	tlrl-tl8506
ODN 1826	TLR9 agonist	Class B CpG oligonucleotide Mouse specific	EndoFit™	1 - 5 μM	200 μg 1 mg 5 mg	tlrl-1826 tlrl-1826-1 tlrl-1826-5
ODN 2006 (ODN 7909)	TLR9 agonist	Class B CpG oligonucleotide Human specific	EndoFit™	1 - 5 μM	200 μg 1 mg 5 mg	tlrl-2006 tlrl-2006-1 tlrl-2006-5
ODN 2216	TLR9 agonist	Class A CpG oligonucleotide Human specific	EndoFit™	1 - 5 μM	200 μg 1 mg 5 mg	tlrl-2216 tlrl-2216-1 tlrl-2216-5
ODN 2395	TLR9 agonist	Class C CpG oligonucleotide Human/Mouse	EndoFit™	1 - 5 μM	200 μg 1 mg 5 mg	tlrl-2395 tlrl-2395-1 tlrl-2395-5

NLR LIGANDS_NLRP3 Inflammasome Inducers

Product	Origin/Description	Endotoxin level	Working conc.	Qty	Cat no.
Nigericin	Nigericin, sodium salt	EndoFit™	1 μM	10 mg 50 mg	tlrl-nig tlrl-nig-5
MSU Crystals	Monosodium urate (uric acid)	EndoFit™	50 - 200 μg/ml	5 mg 25 mg	tlrl-msu tlrl-msu-25
CPPD Crystals	Calcium pyrophosphate dihydrate	EndoFit™	50 - 200 μg/ml	5 mg	tlrl-cppd
Chitosan Ultrapure	Deacetylated derivative of chitin	EndoFit™	10 - 100 μg/ml	100 mg	tlrl-cht
Chitosan VacciGrade™	Preclinical grade deacetylated derivative of chitin	EndoFit™	100 μg/mouse	100 mg	vac-cht
ATP	Adenosine 5’-triphosphate disodium salt	EndoFit™	5 mM	1 g	tlrl-atp

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CLR, RLR & CDS Signaling Pathways InvivoGen의 Reporter Cell Lines

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