Adjuvant Application in Bacterial Infection |
| Application | Vaccine Formulation (F) / Vaccination Protocol (P) | PMID |
| Acinetobacter | F: 10μg antigen was formulated with AddaS03™ at a 1:1 volume ratio.
P: Mice were subcutaneously injected with vaccines on day 0 ,14 and 28. | 38675740 |
| Brucellosis | F: 20 or 60μg antigen was combined with AddaVax™ or Alhydrogel® adjuvant 2%.
P: Mice were intraperitoneally injected vaccine at days 0, 14, and 28 thrice. | 25930114 |
| Burkholderia mallei | F: 1e6 cfu/ml of heat-inactivated B. mallei was formulated with IFA.
P: Horses were subcutaneously immunized with 1ml vaccine for 1, 14, 28 days. | 31523407 |
| Campylobacter jejuni | F: 25μg CPSconj was mixed with 100μl AddaVax™.
P: Chicks were subcutaneously injected with 200μl vaccine at 7 days post-hatch, and received a booster containing 10μg antigen at 21 days post-hatch. | 26032784 |
| GAS | F: 5μg recombinant antigen was formulated in 1:1 AddaVax™.
P: Mice were subcutaneously injected at the base of the tail thrice with a two week interval. |
26911649 |
| H. ducreyi | F: 0.04-100μg protein was formulated with 40μg Imiquimod VacciGrade™, Alhydrogel® adjuvant 2% at a 1:1 ratio, 10μg MPLAs Vaccigrade™, or 30μg ODN 1826 VacciGrade™.
P: Mice were either subcutaneously or intramuscularly injected three doses at three-week intervals. | 26812077 |
Necrotic
enteritis | F: 50μg recombination peptide was mixed with 50μg Quil-A® adjuvant.
P: Broiler chickens were injected intramuscularly with 200μl vaccine at pectoral muscle on days 7,14, and 21. | 37958078
37002317 |
Staphylococcus
aureus | F: Combination of 3 proteins antigens was mixed with 0.1% Alhydrogel in PBS plus 50μg Imiquimod VacciGrade™, 100μg WGP Dispersible, or 10μg MPLAs Vaccigrade™.
P: Mice were subcutaneously injected with 200μl vaccine at days 0 and 21. | 31181086 |
| Tuberculosis | F: 10μg protein was mixed with 1μg Quil-A® adjuvant.
P: Mice were subcutaneously injected thrice at 3 weeks interval. | 38124744 |
| Tularemia | F: Each vaccine dose contained 200μg GLP, 10μg peptide antigen, 50μg mouse serum albumin, and 10μg Imiquimod VacciGrade™.
P: Rats were subcutaneously received three immunisation 2 weeks apart with 100μl vaccine. | 38713688 |
| UTI | F: Nanofibers containning 5mM antigens were mixed with 10μg c-di-AMP VacciGrade™, and combined with or withour 25μg ODN 1826 / 20μg CRX-527, respectively.
P: Mice were sublingually iadministrated with vaccines and boosted at weeks 1, 3, 6, and 10. | 36417519 |
| UTI | F: Nanofibers containning 5mM antigens were mixed with 10μg c-di-AMPVacciGrade™ and 25μg ODN 1826.
P: Rabbits were immunized with vaccine tablets placed under the tougue and boosted at weeks 2, 4, 7, and 10. | 36417519 |
이전 내용 : Adjuvant Application in Virus Infection <- 링크
P: Mice were subcutaneously injected with vaccines on day 0 ,14 and 28.
P: Mice were intraperitoneally injected vaccine at days 0, 14, and 28 thrice.
P: Horses were subcutaneously immunized with 1ml vaccine for 1, 14, 28 days.
P: Chicks were subcutaneously injected with 200μl vaccine at 7 days post-hatch, and received a booster containing 10μg antigen at 21 days post-hatch.
P: Mice were subcutaneously injected at the base of the tail thrice with a two week interval.
26911649
P: Mice were either subcutaneously or intramuscularly injected three doses at three-week intervals.
enteritis
P: Broiler chickens were injected intramuscularly with 200μl vaccine at pectoral muscle on days 7,14, and 21.
37002317
aureus
P: Mice were subcutaneously injected with 200μl vaccine at days 0 and 21.
P: Mice were subcutaneously injected thrice at 3 weeks interval.
P: Rats were subcutaneously received three immunisation 2 weeks apart with 100μl vaccine.
P: Mice were sublingually iadministrated with vaccines and boosted at weeks 1, 3, 6, and 10.
P: Rabbits were immunized with vaccine tablets placed under the tougue and boosted at weeks 2, 4, 7, and 10.
P: Mice were subcutaneously injected with vaccines.
contortus
P: Goats were subcutaneously injected three times at days 0, 21, and 42.
P: Mice were subcutaneously injected at the base of the tail thrice with a two-week interval.
P: Rats were subcutaneously injected with 100μl vaccines on day 0 and 21.
P: Rabbits were immunized subcutaneously in one site in the dorsal area with 500μl vaccine on day 0 and day 21.
P: Rats were subcutaneously injected with vaccines on day 0 and boosted twice after the initial prime on days 21 and 42.
P: Rats were subcutaneously injected in one site in the inguinal region with 100μl vaccines twice on day 0 and 21 or three times on days 0, 21 and 42.
P: Rabbits were immunized subcutaneously in one site in the dorsal area with 500μl vaccine on day 0 and day 21.
P: Mice were intramuscularly injected into each rear leg on days 0 and 17.
P: Mice were intraperitoneally injected with three 100μl doses at days 0, 15, and 30.
P: Mice were intramuscularly injected with 50μl vaccine at the right posterior tibialis muscle.
P: Mice were intratumorally injected with adjuvant on days 5 and 8, and peptides on days 6 and 9.
P: Mice were intravenously inejcted with vaccines every other day.
P: Mice were intraperitoneally injected every 5 days from days 21 after tumor tansplantation.
P: Mice were intramuscularly injected with 50μl vectors at 1e7 or 1e9 viral particles, and subcutaneously injected with 100μl mixed adjuvants at the tail base at days 0, 14, and 28.
P: Mice were intratumorally injected with adjuvant on days 10 and 13, and peptideson days 11 and 14.
P: Mice were subcutaneously injected with 100μl vaccine at the base of the tail on days 3 and 10.
P: Mice were subcutaneously injected with vaccines at days 0 and 14.
P: Mice were intraperitoneally injected vaccine at the 9th week and boosted fortnightly up to 15th week.
P: Mice were intra-articularly injected daily up tp 3 days.
P: Mice were intraperitoneally injected with vaccine on days 0 and 6.
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