Product | Description | Qty | Cat no. |
THP1 | | | |
THP1-Dual™ Cells | NF-κB-SEAP IRF-Luc Reporter Monocytes | 3-7 x 10e6 cells | thpd-nfis |
THP1-Dual™ KO-STING Cells | Human THP-1 Monocytes - STING knockout NF-κB-SEAP and IRF-Lucia Reporter Cells | 3-7 x 10e6 cells | thpd-kostg |
THP1-Dual™ KO-cGAS Cells | cGAS knockout NF-κB-SEAP and IRF-Lucia reporter cells | 3-7 x 10e6 cells | thpd-kocgas |
THP1-Dual™ KO-IFI16 cells | IFI16 knockout NF-κB-SEAP and IRF-Lucia reporter cells | 3-7 x 10e6 cells | thpd-koifi16 |
THP1-Dual™ KO-IRF3 Cells | IRF3 knockout NF-κB-SEAP and IRF-Lucia reporter cells | 3-7 x 10e6 cells | thpd-koirf3 |
THP1-Dual™ KO-TBK1 Cells | TBK1 knockout NF-κB-SEAP and IRF-Lucia reporter cells | 3-7 x 10e6 cells | thpd-kotbk |
THP1-Dual™ KO-TREX1 Cells | TREX1 knockout NF-κB-SEAP and IRF-Lucia reporter cells | 3-7 x 10e6 cells | thpd-kotrex |
THP1-Dual™ KI-hSTING-S154 Cells | STING (N154S isoform; constitutively active) knockin NF-kB-SEAP and IRF-Lucia Reporter Monocytes | 3-7 x 10e6 cells | thpd-s154 |
THP1-Dual™ KI-hSTING-M155 Cells | STING (V155M isoform; constitutively active) knockin NF-kB-SEAP and IRF-Lucia Reporter Monocytes | 3-7 x 10e6 cells | thpd-m155 |
THP1-Dual™ KI-hSTING-A162 Cells | STING (A162 isoform) knockin NF-kB-SEAP and IRF-Lucia Reporter Monocytes | 3-7 x 10e6 cells | thpd-a162 |
THP1-Dual™ KI-hSTING-H232 Cells | Human THP-1 Monocytes - STING (H232 isoform) knockin NF-kB-SEAP and IRF-Lucia Reporter Cells | 3-7 x 10e6 cells | thpd-h232 |
THP1-Dual™ KI-hSTING-R232 Cells | STING (R232 isoform) knockin NF-kB-SEAP and IRF-Lucia Reporter Monocytes | 3-7 x 10e6 cells | thpd-r232 |
THP1-Dual™ KI-mSTING Cells | Murine STING knockin NF-kB-SEAP and IRF-Lucia Luciferase Reporter Monocytes | 3-7 x 10e6 cells | thpd-mstg |
293T | | | |
293-Dual™ hSTING-A162 Cells | 293-Dual™ hSTING-A162 Cells | 3-7 x 10e6 cells | 293d-a162 |
293-Dual™ hSTING-H232 Cells | 293-Dual™ hSTING-H232 Cells | 3-7 x 10e6 cells | 293d-h232 |
293-Dual™ hSTING-R232 Cells | 293-Dual™ hSTING-R232 Cells | 3-7 x 10e6 cells | 293d-r232 |
293-Dual™ mSTING Cells | 293-Dual™ mSTING Cells | 3-7 x 10e6 cells | 293d-mstg |
293-Dual™ Null Cells | 293-Dual™ Null Cells | 3-7 x 10e6 cells | 293d-null |
HEK293 | | | |
HEK-Blue™ ISG Cells | IFN Regulatory Factor (IRF)-Inducible SEAP Reporter HEK293 Cells | 3-7 x 10e6 cells | hkb-isg-1 |
HEK-Blue™ ISG-KO-STING Cells | HEK293 - STING Knockout IRF-reporter cells | 3-7 x 10e6 cells | hkb-isgkostg |
HEK-Blue™ STAT6-hSTING-R232 Cells | Human STING (R232 variant)-dependent STAT6 HEK293 reporter cells | 3-7 x 10e6 cells | hkb-st6r232 |
Murine B16 melanocytes | | | |
B16-Blue™ ISG Cells | Murine B16 melanoma - IFNs reporter cells | 3-7 x 10e6 cells | bb-ifnabg |
B16-Blue™ ISG-KO-STING Cells | Murine B16 melanoma - STING Knockout IRF-reporter cells | 3-7 x 10e6 cells | bb-kostg |
Murine RAW 264.7 macrophages | | | |
RAW-Lucia™ ISG Cells | Mouse Macrophages - CDS Reporter Cells | 3-7 x 10e6 cells | rawl-isg |
RAW-Lucia™ ISG-KO-STING Cells | Murine RAW 264.7 macrophages - STING Knockout IRF-reporter cells | 3-7 x 10e6 cells | rawl-kostg |
RAW-Lucia™ ISG-KO-cGAS Cells | cGAS knockout IRF-Lucia reporter cells | 3-7 x 10e6 cells | rawl-kocgas |
RAW-Lucia™ ISG-KO-IFI16 Cells | IFI16 knockout IRF-Lucia reporter cells | 3-7 x 10e6 cells | rawl-koif16 |
RAW-Lucia™ ISG-KO-IRF3 Cells | IRF3 knockout IRF-Lucia reporter cells | 3-7 x 10e6 cells | rawl-koirf3 |
RAW-Lucia™ ISG-KO-TBK1 Cells | TBK1 knockout IRF-Lucia reporter cells | 3-7 x 10e6 cells | rawl-kotbk |
RAW-Lucia™ ISG-KO-TREX1 Cells | TREX1 knockout IRF-Lucia reporter cells | 3-7 x 10e6 cells | rawl-kotrex |
STING Ligand, Cyclic dinucleotides (CDNs) and Xanthenone derivative (DMXAA)
Cyclic dinucleotides(CDNs)와 xanthenone derivative DMXAA는 STING에 binding 하여 강한 반응을 일으키는 것으로 알려져 있습니다.
CDNs는 prokaryotic cell의 수많은 반응에 영향을 미치는 박테리아의 중요한 메신져이며, mammalian cell 에서는 선천 면역 반응의 강력한 유도제이므로 CDNs은 새롭게 각광받는 vaccine adjuvant 이기도 합니다.
InvivoGen은 두가지 grade의 CDNs를 공급하고 있습니다.
- InvivoGen Standard Grade: purity ≧ 95%, validated using cell-based assays
- VacciGrade™: sterility guaranteed and endotoxin level < 1 EU/mg, in addition to the above-mentioned criteria
* STING에 대한 더 자세한 정보는 첨부파일 및 아래 동영상 세미나를 통해 확인하실 수 있습니다.
* 아래 그림을 클릭하여 STING 동영상 세미나를 다운받으실 수 있습니다.
*Read our review on STING: Deciphering the STING Paradox
STING Ligand
STING Inhibitor
STING Reporter Cells
STING Variants
STING Antibody
#invivogen #다윈바이오 #TLR #toll-like receptor #ligand
[학술문의] T. 031-728-3236 E. technical@dawinbio.com