Cell LinesReporter Cell Lines

InvivoGen 에서는 innate immunity-specific signaling pathway 연구를 위한 가장 다양한 cell line을 공급하고 있습니다. 

SEAP(secreted embryonic alkaline phosphatase) 혹은 Luciferase가 단독 혹은 동시에 발현되며,  세포 밖으로 분비되는 결과를 측정하게 됩니다. 

간단하고 쉽게 detection을 하기 위한 reagent를 개발하여 함께 제공하고 있습니다 

SEAP monitoring : HEK-Blue™ 와 QUANTI-Blue™ 를 통해 spectrophotometer 로 확인

Lucia luciferase monitoring : QUANTI-Luc™ 과 QUANTI-Gold™ 를 사용하여 luminometer 로 확인

 

Six major families of reporter cells are available to meet your research needs:

  • PRR reporter cells (TLRs, CLRs, CDSs & STING, NLRs, RLRs, AhR, inflammasomes)
  • Transcription factor reporter cells (NF-κB and/or IRF pathways)
  • Cytokine reporter cells
  • Autophagy reporter cells
  • Knock-out reporter cells


Cell lineDescriptionCat no.
A549-Dual™ Cells Human NF-κB-SEAP & IRF-Luc Reporter lung carcinomaa549d-nfis
A549-Dual™ KO-MAVS Cells 
MAVS knockout NF-kB-SEAP & IRF-Lucia Reporter Cell Linea549d-komavs
A549-Dual™ KO-MDA5 Cells 
MDA-5 knockout NF-kB-SEAP & IRF-Lucia Reporter Cell Linea549d-komda5
A549-Dual™ KO-RIG-I Cells 
RIG-I knockout NF-kB-SEAP & IRF-Lucia Reporter Cell Linea549d-korigi


Cell lineDescription
B16-Blue™ IFN-α/β Cells Murine B16 melanoma - Type I IFNs reporter cells
B16-Blue™ IFN-γ Cells Murine B16 melanoma - IFNγ reporter cells
B16-Blue™ ISG Cells Murine B16 melanoma - IFNs reporter cells
B16-Blue™ ISG-KO-STING Cells Murine B16 melanoma - STING Knockout IRF-reporter cells


Cell lineDescription
HCT116-Dual™ CellsHuman NF-κB-SEAP & IRF-Luc Reporter colorectal carcinoma


HEK CLR Reporter Cells 
CLR SEAP Reporter HEK 293
Cell lineDescription
HEK-Blue™ hDectin-1a Cells Human Dectin-1a / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ hDectin-1b Cells Human Dectin-1b / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ mDectin-1b Cells Murine Dectin-1b / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ mDectin-2 Cells Murine Dectin-2 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ mMincle Cells Murine Mincle / NF-κB / SEAP reporter HEK293 cells
HEK NOD Reporter Cells 
NOD SEAP Reporter HEK 293
Cell lineDescription
HEK-Blue™ hNOD1 Human NOD1 / NF-kB / SEAP reporter HEK293 cells
HEK-Blue™ mNOD1 Murine NOD1 / NF-kB / SEAP reporter HEK293 cells
HEK-Blue™ hNOD2 Human NOD2 / NF-kB / SEAP reporter HEK293 cells
HEK-Blue™ mNOD2 Murine NOD2 / NF-kB / SEAP reporter HEK293 cells
HEK RLR Reporter Cells 
RLR Lucia Reporter HEK 293
Cell lineDescription
HEK-Lucia™ RIG-I Cells Lucia luciferase reporter HEK293 cells expressing human RIG-I
HEK-Lucia™ Null Cells Lucia luciferase reporter HEK293 cells
HEK STING Reporter Cells 
STING SEAP Reporter 293T
Cell lineDescription
293T-Dual™ hSTING-A162 Cells Dual IRF and IFN-β reporter 293T cells expressing A162 isoform of human STING (S162A)
293T-Dual™ hSTING-H232 Cells Dual IRF and IFN-β reporter 293T cells expressing H232 isoform of human STING (R232H)
293T-Dual™ hSTING-R232 Cells Dual IRF and IFN-β reporter 293T cells expressing R232 isoform of human STING
293T-Dual™ mSTING Cells Dual IRF and IFN-β reporter 293T cells expressing murine STING
293T-Dual™ Null Cells Dual IRF and IFN-β reporter 293T cells
HEK TLR Reporter Cells 
TLR SEAP Reporter HEK 293
Cell lineDescription
HEK-Blue™ (NFkB-SEAP) TLR cells
HEK-Blue™ hMD2-CD14 Human MD2-CD14 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ hTLR2Human TLR2 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ hTLR2-TLR1 Cells Human TLR2+TLR1 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ hTLR2-TLR6 Cells Human TLR2+TLR6 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ hTLR2 KO-TLR1/6 Cells Human TLR2 (KO-TLR1/6) / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ mTLR2 Murine TLR2 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ hTLR3 Human TLR3 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ mTLR3 Murine TLR3 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ hTLR4 Human TLR4 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ mTLR4 Murine TLR4 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ hTLR5 Human TLR5 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ mTLR5 Murine TLR5 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ hTLR7 Human TLR7 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ mTLR7 Murine TLR7 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ hTLR8 Human TLR8 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ mTLR8 Murine TLR8 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ hTLR9 Human TLR9 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ mTLR9 Murine TLR9 / NF-κB / SEAP reporter HEK293 cells
HEK-Blue™ mTLR13 Murine TLR13 / NF-κB / SEAP reporter HEK293 cells
HEK-DUAL™ (NFKB-SEAP / KI-[IL-8]Lucia) TLR CELLS
Cell lineDescription
HEK-Dual™ hTLR2 Human TLR2 (NF-κB-SEAP / KI-[IL-8]Lucia) dual-reporter HEK293 cells
HEK-Dual™ hTLR3 Human TLR3 (NF-κB-SEAP / KI-[IL-8]Lucia) dual-reporter HEK293 cells
HEK-Dual™ mTLR4 Murine TLR4 (NF-κB-SEAP / KI-[IL-8]Lucia) dual-reporter HEK293 cells
HEK-Dual™ hTLR5 Human TLR5 (NF-κB-SEAP / KI-[IL-8]Lucia) dual-reporter HEK293 cells
HEK-Dual™ mTLR7 Murine TLR7 (NF-κB-SEAP / KI-[IL-8]Lucia) dual-reporter HEK293 cells
HEK-Dual™ hTLR9 Human TLR9 (NF-κB-SEAP / KI-[IL-8]Lucia) dual-reporter HEK293 cells
HEK-Dual™ Null NF-κB-SEAP / KI-[IL-8]Lucia dual-reporter HEK293 cells
HEK Cytokine Reporter Cells 
Cytokines Reporter HEK 293
Interferon Reporter Cells
Cell lineDescription
HEK-Blue™ IFN-α/β Cells Human HEK293 cells - Type I IFNs reporter cells
HEK-Blue™ IFN-γ Cells Human HEK293 cells - Type II IFNs reporter cells
HEK-Dual™ IFN-γ Cells Human IFN-γ SEAP/Luciferase reporter HEK293 cells
HEK-Blue™ IFN-λ Cells Human HEK293 cells - Type III IFNs reporter cells
HEK-Blue™ ISG Cells Interferon Regulatory Factor (IRF)-Inducible SEAP Reporter HEK293 Cells
Interleukin Reporter Cells
Cell lineDescription
HEK-Blue™ IL-1β Cells Human & Mouse IL-1β Sensor Cells
HEK-Blue™ IL-1R Cells Human & Mouse IL-1 Sensor Cells
HEK-Blue™ IL-2 Cells Human & Mouse IL-2 Reporter Cells
HEK-Blue™ IL-4/IL-13 Cells Human IL-4 / IL-13 SEAP reporter HEK293 cells | JAK/STAT6 pathway
HEK-Blue™ IL-6 Cells Human IL-6 Sensor Cells
HEK-Blue™ IL-12 Cells Human & Mouse IL-12 Sensor Cells
HEK-Blue™ IL-17 Cells Human & Mouse IL-17 Reporter Cells, HEK-Blue™ IL-17 Cells
HEK-Blue™ IL-18 Cells Human & Mouse IL-18 Sensor Cells
HEK-Blue™ IL-33 Cells Human IL-33 Sensor Cells
Tumor Growth Factor Reporter Cells
Cell lineDescription
HEK-Blue™ TGF-β Cells Human TGFβ SEAP reporter HEK293 cells
Tumor Necrosis Factor Reporter Cells
Cell lineDescription
HEK-Blue™ TNF-α Cells Human TNF-α SEAP reporter HEK293 cells NF-κB/AP-1 pathway
HEK-Dual™ TNF-α Cells Human and Murine TNF-α SEAP / luciferase reporter HEK293 cells - NF-κB pathway
HEK-Blue™ CD40L Cells Human CD40L SEAP reporter HEK293 cells
HEK NF-κB Reporter Cells NF-kB SEAP Reporter HEK 293 - parental cell lines
Cell lineDescription
HEK-Blue™ Null1 Cells NF-kappaB / SEAP parental cell line
HEK-Blue™ Null1-k cells NF-kappaB / SEAP parental cell line
HEK-Blue™ Null1-v cells NF-kappaB / SEAP parental cell line
HEK-Blue™ Null2-k cells NF-kappaB / SEAP parental cell line
HEK-Blue™ Null2 cells NF-kappaB / SEAP parental cell line


Cell lineDescription
HeLa-Difluo™ hLC3 cellsAutophagy Reporter Cells


Cell lineDescription
HepG2-Dual™ Cells NFkB-SEAP & IRF-Lucia reporter liver carcinoma cells
HepG2-Lucia™ AhR Cells [NEW] Human HepG2 liver carcinoma - AhR-Lucia reporter cells


Cell lineDescription
HT29-Lucia™ AhR CellsHuman HT29 colon adenocarcinoma - AhR reporter cells


Cell lineDescription
J774-Dual™ CellsMurine NF-kB & IRF Reporter macrophage-like cells


Cell lineDescription
Jurkat-Dual™ Cells Human T Lymphocytes - NF-kB/IRF reporter cells
Jurkat-Lucia™ NFAT Cells NFAT-Luc Reporter T Lymphocytes
Jurkat-Lucia™ NFAT-CD16 Cells [NEW] Human T Lymphocytes - ADCC Reporter Cells


Cell lineDescription
Ramos-Blue™ Cells NF-kB/AP-1 reporter B lymphocytes
Ramos-Blue™ KD-MyD Cells NF-κB/AP-1 SEAP reporter B lymphocytes with MyD88 knockdown


NF-κB-Reporter Cells
Cell lineDescription
RAW-Blue™ Cells NF-κB-SEAP Reporter Cell Line
IRF-Reporter Cells
Cell lineDescription
RAW-Blue™ ISG Cells IRF-SEAP-Reporter Cell Line
RAW-Lucia™ ISG Cells IRF-Lucia Luciferase Reporter Cell Line
IRF/KIN-MIP2 -Reporter Cells
Cell lineDescription
RAW-Dual™ Cells Dual IRF and NF-kB Reporter Cell Line
Knockout Cells
Cell lineDescription
RAW-Dual™ KO-TLR4 Cells TLR4 knockout IRF-Lucia Luciferase Reporter Cell Line
RAW-Lucia™ ISG-KO-cGAS Cells cGAS Knockout IRF-Lucia Luciferase Reporter Cell Line
RAW-Lucia™ ISG-KO-IFI16 Cells IFI16 Knockout IRF-Lucia Luciferase Reporter Cell Line
RAW-Lucia™ ISG-KO-IRF3 Cells IRF3 Knockout IRF-Lucia Luciferase Reporter Cell Line
RAW-Lucia™ ISG-KO-IRF7 Cells IRF7 Knockout IRF-Lucia Luciferase Reporter Cell Line
RAW-Lucia™ ISG-KO-MAVS Cells MAVS-Knockout IRF-Lucia Luciferase Reporter Cell Line
RAW-Lucia™ ISG-KO-MDA5 Cells MDA-5 Knockout IRF-Lucia Luciferase Reporter Cell Line
RAW-Lucia™ ISG-KO-RIG-I Cells RIG-I Knockout IRF-Lucia Luciferase Reporter Cell Line
RAW-Lucia™ ISG-KO-STING Cells STING Knockout IRF-Lucia Luciferase Reporter Cell Line
RAW-Lucia™ ISG-KO-TBK1 Cells TBK1 Knockout IRF-Lucia Luciferase Reporter Cell Line
RAW-Lucia™ ISG-KO-TREX1 Cells TREX1 Knockout IRF-Lucia Luciferase Reporter Cell Line
RAW-Lucia™ ISG-KO-TRIF Cells TRIF Knockout IRF-Lucia Luciferase Reporter Cell Line
Autophagy Reporter Cells
Cell lineDescription
RAW-Difluo™ mLC3 Cells Autophagy Reporter Cells


NF-κB Reporter Monocytes
Cell lineDescription
THP1-Blue™ NF-κB Cells Human THP-1 Monocytes - NF-kB SEAP Reporter
THP1-Lucia™ NF-κB Cells Human THP-1 Monocytes - NF-κB Luc Reporter Monocytes
IRF Reporter Monocytes
Cell lineDescription
THP1-Blue™ ISG Cells Human THP-1 Monocytes - IRF SEAP Reporter
THP1-Lucia™ ISG Cells Human THP-1 Monocytes - IRF Luciferase Reporter Cells
THP1-Blue™ KI-IP10 Cells [NEW] Human THP-1 Monocytes - ISG Luciferase Reporter Cells
NF-κB and IRF Reporter Monocytes
Cell lineDescription
THP1-Dual™ Cells Human THP-1 Monocytes - NF-κB-SEAP IRF-Luc Reporter
THP1-Dual™ KO-cGAS Cells Human THP-1 Monocytes - cGAS knockout NF-κB-SEAP and IRF-Lucia Reporter Cells
THP1-Dual™ KO-IFI16 Cells Human THP-1 Monocytes - IFI16 knockout NF-κB-SEAP and IRF-Lucia Reporter Cells
THP1-Dual™ KO-IFNAR2 Cells Human THP-1 Monocytes - IFNAR2 knockout NF-κB-SEAP and IRF-Lucia Reporter Cells
THP1-Dual™ KO-MyD Cells Human THP-1 Monocytes - MyD88 knockout NF-κB-SEAP and IRF-Lucia Reporter Cells
THP1-Dual™ KO-STING Cells Human THP-1 Monocytes - STING knockout NF-κB-SEAP and IRF-Lucia Reporter Cells
THP1-Dual™ KI-hSTING-S154 Cells Human THP-1 Monocytes - STING (S154 isoform; constitutively active) knockin NF-kB-SEAP and IRF-Lucia Reporter Cells
THP1-Dual™ KI-hSTING-M155 Cells Human THP-1 Monocytes - STING (M155 isoform; constitutively active) knockin NF-kB-SEAP and IRF-Lucia Reporter Cells
THP1-Dual™ KI-hSTING-A162 Cells Human THP-1 Monocytes - STING (A162 isoform) knockin NF-kB-SEAP and IRF-Lucia Reporter Cells
THP1-Dual™ KI-hSTING-H232 Cells Human THP-1 Monocytes - STING (H232 isoform) knockin NF-kB-SEAP and IRF-Lucia Reporter Cells
THP1-Dual™ KI-hSTING-R232 Cells Human THP-1 Monocytes - STING (R232 isoform) knockin NF-kB-SEAP and IRF-Lucia Reporter Cells
THP1-Dual™ KO-TREX1 Cells Human THP-1 Monocytes - TREX1 knockout NF-κB-SEAP and IRF-Lucia Reporter Cells
Inflammasome Test Cells
Cell lineDescription
THP1-ASC-GFP Cells Human THP-1 Monocytes - ASC speck reporter cells
THP1-defASC Cells Human THP-1 Monocytes - ASC-deficient
THP1-defCASP1 Cells Human THP-1 Monocytes - caspase-1 deficient
THP1-defNLRP3 Cells Human THP-1 Monocytes - NLRP3-deficient
THP1-HMGB1-Lucia™ Cells Pyroptosis and necroptosis reporter monocytes
THP1-NLRC4 Cells Human THP-1 Monocytes - NLRC4 inflammasome test
THP1-Null Cells Human THP-1 Monocytes - Positive Control for Inflammasome Studies
Autophagy Reporter Cells
Cell lineDescription
THP1-Difluo™ hLC3 Cells Autophagy reporter cells


- InvivoGen 에서 판매하는 cell line은 LMO 신고 후에 구매가 가능합니다.

- 모든 세포는 실온(flask)으로 배송되고 있습니다. 


* 학술 문의   T.  031-728-3231   E.  technical@dawinbio.com

The selective antibiotics of choice

  • Blasticidin
  • G418 Sulfate
  • Hygromycin B Gold
  • Phleomycin
  • Puromycin
  • Zeocin™

Save your valuable cell lines with:

  • PlasmoTest™
  • Plasmocin™
  • Plasmocure™
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