Antibodies & ELISAsCOVID-19 Related Products

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COVID-19

SARS-CoV-2 (2019-nCoV)는 highly-pathogenic β-coronavirus로 인해 발생한 3번째 질병입니다. 이는 종들 사이의 바이러스 감염주기, 바이러스 복제에 관련된 세포 경로, 선천 혹은 후천 면역 반응에 대해 심도 있는 지식을 필요로 하는 것을 의미합니다. 이러한 근본적인 질문에 대한 답변은 예방백신은 물론 안전하고 효율적인 치료법 설계에 도움이 될 것입니다.

아래 동영상으로도 Invivogen의 제품을 확인할 수 있습니다. 


COVID-19-Related Products

*제품을 클릭하시면 상세 페이지를 확인하실 수 있습니다. 

COVID-19-Related Genes
SARS-CoV-2 Cellular Receptor Genes 
• SARS-CoV-2 Structural Genes   
COVID-19-Related Inhibitors
• Viral RdRp Inhibitor
-  Remdesivir 
  
Other COVID-19-Related Products
• Type I IFN Inducers 
 -  Poly(I:C)
COVID-19-Related Antibodies
• Anti-SARS-CoV-2 Antibodies   
• JAK/STAT Signaling Inhibitors
-  Ruxolitinib  
 -  3p-hpRNA
• Fc-Fusion
 Anti-hIL6R mabs (Tocilizumab)
COVID-19-Related Proteins
• Spike 
• Endosomal Acidification Inhibitors
- Chloroquine 
Bafilomycin A1    
-  pFUSE-Fc plasmids
• Antibody Generation
-  pFUSE
• Human ACE2
 Nucleocapsid
 Human ACE2

-  pTRIOZ 
• Vaccine Adjuvants
-  Alum, emulsions, and PRR agonists

COVID-19-Related Genes (Vector)

Product nameUnit sizeCat.no
pUNO1-hACE220 µg puno1-hace2
pUNO1-hTMPRSS2a20 µg puno1-htps2a
pUNO1-hTMPRSS2b20 µg puno1-htps2b
pDUO2-hACE2-TMPRSS2a20 µg pduo2-hace2tpsa
pUNO1-SARS2-S20 µg puno1-cov2-s
pUNO1-SARS2-E20 µg puno1-cov2-e
pUNO1-SARS2-M20 µg puno1-cov2-m
pUNO1-SARS2-N20 µg puno1-cov2-n
pUNO1His-SARS2-S20 µg p1his-cov2-s
pUNO1Fc-SARS2-S20 µg p1fc-cov2-s
pUNO1His-SARS2-S120 µg p1his-cov2-s1
pUNO1Fc-SARS2-S120 µg p1fc-cov2-s1
pUNO1His-SARS2-RBD20 µg p1his-cov2-rbd
pUNO1Fc-SARS2-RBD20 µg p1fc-cov2-rbd
pUNO1-SARS2-S (D614G)20 µgpuno1-cov2-sg


COVID-19-Related Antibodies

Product name
QUALITY CONTROL
Unit size
Cat.no
Anti-Spike-RBD hIgG1 (CR3022)Functionality validated by ELISA using a coated Spike-RBD-His fusion peptide100 µg srbd-mab1
Anti-Spike-RBD hIgA1 (CR3022)Functionality validated by ELISA using a coated Spike-RBD-His fusion peptide
100 µg srbd-mab6
Anti-Spike-RBD hIgM (CR3022)Functionality validated by ELISA using a coated Spike-RBD-His fusion peptide
100 µg srbd-mab5
Anti-Spike-RBD hIgG1NQ (CR3022)Functionality validated by ELISA using a coated Spike-RBD-His fusion peptide
100 µg srbd-mab12
Anti-Spike-RBD mIgG2a (CR3022)Functionality validated by ELISA using a coated Spike-RBD-His fusion peptide
100 µg srbd-mab10
Anti-Spike-RBD mIgG1e3 (CR3022)Functionality validated by ELISA using a coated Spike-RBD-His fusion peptide
100 µg srbd-mab15
Anti-hIL6R-To-hIgG1Functionally validated using HEK-Blue™ IL-6 cellular assays100 µg hil6rto-mab1
Anti-hIL6R-To-hIgG1NQFunctionally validated using HEK-Blue™ IL-6 cellular assays
100 µg hil6rto-mab12
Anti-hIL6R-To-hIgA2Functionally validated using HEK-Blue™ IL-6 cellular assays
100 µg hil6rto-mab7
Anti-Spike-RBD-hIgG1-HRPFunctionality validated by ELISA using a coated Spike-RBD-His fusion peptide
100µgsrbd-mab1-hrp
Anti SARS-CoV-2 RBD mAb (Clone H4)Functionality validated by ELISA using a coated Spike-RBD-His fusion peptide
100 µg cov2rbdc1-mab1
Anti SARS-CoV-2 RBD mAb (Clone B38)Functionality validated by ELISA using a coated Spike-RBD-His fusion peptide
100 µg cov2rbdc2-mab1
Anti SARS-CoV-2 Nucleocapsid mAb
(clone CR3018)
Functionality validated by ELISA using a coated Spike-RBD-His fusion peptide
100 µg covn-mab1


COVID-19-Related Proteins

Product name
QUALITY CONTROL
Unit size
Cat.no
Spike RBD-HisProtein validated by ELISA using a coated Anti-SARS-CoV-Spike-RBD hIgM mAb (clone CR3022)50 µghis-sars2-rbd
Spike RBD-FcProtein validated by ELISA using a coated Anti-SARS-CoV-Spike-RBD hIgM mAb (clone CR3022)
50 µgfc-sars2-rbd
hACE2-FcProtein validated by ELISA upon incubation with a coated Spike-RBD-His protein and an Anti-human IgG1-HRP detection antibody50 µgfc-hace2
Spike-S1-HisProtein validated by ELISA using a coated Anti-SARS-CoV-Spike-RBD hIgM mAb (clone CR3022)
50 µghis-sars2-s1
Spike-S1-FcProtein validated by ELISA using a coated Anti-SARS-CoV-Spike-RBD hIgM mAb (clone CR3022)
50 µgfc-sars2-s1
Nucleocapsid-HisProtein validated by ELISA using a coated Anti-SARS Nucleocapsid 50 µghis-sars2-n
Nucleocapsid-Fc Protein validated by ELISA using a coated Anti-SARS Nucleocapsid
50 µgfc-sars2-n
Spike-S1-His (D614G)Protein validated by ELISA using a coated Anti-SARS-CoV-Spike-RBD hIgM mAb (clone CR3022)
50 µghis-sars2-s1g
Spike-S1-Fc (D614G)Protein validated by ELISA using a coated Anti-SARS-CoV-Spike-RBD hIgM mAb (clone CR3022)
50 µgfc-sars2-s1g


COVID-19-Related Inhibitors

Product name
Unit sizeCat.no
Remdesivir1 mginh-rem
Ruxolitinib5 mgtlrl-rux
Chloroquine250 mgtlrl-chq
Bafilomycin A110 µgtlrl-baf1


Other COVID-19-Related Products

Poly(I:C): TLR3 agonist

Product nameUnit sizeCat.no
Poly(A:U)10 mg tlrl-pau
Poly(I:C) HMW10 mg tlrl-pic
50 mgtlrl-pic-5
Poly(I:C) (HMW) Biotin10 µg tlrl-picb
Poly(I:C) (HMW), fluorescent10 µg tlrl-picf
Poly(I:C) (HMW) Rhodamine10 µg tlrl-picr
Poly(I:C) (HMW) VacciGrade™10 mg vac-pic
Poly(I:C) LMW25 mg tlrl-picw
250 mgtlrl-picw-250
Poly(I:C) (LMW) Rhodamine10 µg tlrl-piwr

 

3p-hpRNA: RIG-I agonist

Product nameUnit sizeCat.no
3p-hpRNA25 µg tlrl-hprna
4 x 25 µg tlrl-hprna-100
3p-hpRNA/LyoVec™25 µg tlrl-hprnalv
4 x 25 µg tlrl-hprnalv-100

 

pFUSE-Fc plasmids: Cloning vectors for the generation of Fc-Fusion proteins

Plasmid Cloning site / GeneFc RegionIsotypes Available
C-terminal Fc fusions
   
pFUSE-FcCloning sitesNative, No introns- Human IgG1, 2, 3, 4
- Mouse IgG1, 2a, 2b, 3
- Rabbit IgG
- Rat IgG2b
pINFUSE-FcCloning sitesNative, With introns- Human IgG1, 2, 3, 4
- Mouse IgG2b
pFUSE-Fc engineeredCloning sitesEngineered, No introns- Human IgG1, 2, 4
- Mouse IgG1, 2a
pFUSE-Lucia-FcLucia secreted luciferase - Cloning sitesNative, No introns- Human IgG1
- Mouse IgG2a
pFUSE-SEAP-FcSEAPNative, No introns- Human IgG1, 2, 3, 4
- Mouse IgG2a, 2b, 3
- Rabbit IgG
- Rat IgG2b
N-terminal Fc fusions
pFUSEN-FcCloning sitesNative, No introns- Human IgG1,2
- Mouse IgG2a
pFUSEN-Fc engineeredCloning sitesEngineered, No introns- Human IgG1
pFUSEN-Lucia-FcLucia secreted luciferase - Cloning sitesNative, No introns- Human IgG1, 2
- Mouse IgG2a
pFUSEN-Lucia-Fc engineeredLucia secreted luciferase - Cloning sitesEngineered, No introns- Human IgG1

 

Antibody generation

pFUSEConstatnt Region Gene
pFUSE-CLIg familyLight chain expression plasmidmultiple cloning site (MCS)  
pFUSE-CHIg familyHeavy chain expression plasmidmultiple cloning site (MCS)  
pFUSE-Lucia-CHIgheavy chain (CH) of human, mouse, rabbitmultiple cloning site (MCS) Lucia secreted luciferase 
Engineered pFUSE-CHIgheavy chain (CH) of the human IgG1multiple cloning site (MCS)  


pTRIOZ Unit sizeCat.noHeavy chain cassetteLight chain cassette
pTRIOZ-hIgG120 µg ptrioz-higg1Human IgG1Human kappa  
pTRIOZ-hIgG4 (S228P)20 µg ptrioz-higg4spHuman IgG4 (S228P)Human kappa  
pTRIOZ-mIgG1e220 µg ptrioz-migg1e2Murine IgG1e2Murine kappa  
pTRIOZ-mIgG2a20 µg Murine IgG2a Murine kappa  


Vaccine adjuvants

Alum & Emulsions  Generate depots that trap antigens at the injection site for a sustained stimulation of the immune system through an increased recruitment and activation of antigen presenting cells (APCs)
PRR agonists  Effectively activate a local innate immune response, predominantly targeting the APCs, and consequently influencing the necessary adaptive immune responses. Members of nearly all of the PRR families are potential targets for adjuvants.

 

학술 문의    Tel. 031-728-3236 E-mail. technical@dawinbio.com


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