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Biosimillar Abs[Bio X Cell] InVivoSIM™ - 승인된 치료제를 기반으로한 연구용 Biosimilar 항체

Bio X Cell
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InVivoSIM™ - In Vivo용 Biosimilar Antibodies


InVivoSIM™ Biosimilar 항체는 승인된 치료제 기반으로 설계된 단클론 항체입니다.

임상용 의약품을  없이도 비용 효율적인 연구가 가능한 in vivo-ready 항체를 Bio X Cell은 제공합니다.


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InVivoSIM™  항체 품질 TEST


InVivoSIM™
Binding ValidationImmunoblot, Flow Cytometry, ELISA 기반
✓
Murine Pathogen 스크리닝Real-Time PCR 기반
✓
Antibody Aggregation 스크리닝Size exclusion Chromatography 기반
✓
EndotoxinLAL assay 기반≤0.5EU/mg
PuritySDS-PAGE 기반≥95%
Preservative, Stabilizer, and Carrier protein : FREE
✓
In-Vivo용 설계
✓


InVivoSIM™  Antibodies 

TargetCat. NoReference Drug　TargetCat. NoReference Drug
ACVR2ASIM0086Bimagrumab　IL-12 p40SIM0020Ustekinumab
Amyloid-betaSIM0032Lecanemab　IL-13SIM0042Tralokinumab
SIM0047Solanezumab　IL-17ASIM0013Secukinumab
SIM0048Donanemab　SIM0029Ixekizumab
AxlSIM0065Tilvestamab　IL-17RASIM0121Brodalumab
BAFFSIM0055Belimumab　IL1RAPSIM0093Nadunolimab
BCMASIM0056Belantamab　IL-1βSIM0044Canakinumab
C5SIM0011Eculizumab　SIM0049Gevokizumab
CD14SIM0061Atibuclimab　IL-23SIM0025Guselkumab
CD142SIM0084Tisotumab　IL-31RASIM0078Nemolizumab
CD19SIM0075Loncastuximab　IL-33SIM0053Etokimab
CD20SIM0008Rituximab　IL‑3RASIM0080Pivekimab
SIM0089Ofatumumab　IL-4RαSIM0023Dupilumab
SIM0090Ocrelizumab　IL-6SIM0030Siltuximab
SIM0091Ublituximab　IL-6RSIM0014Tocilizumab
CD25SIM0035Daclizumab　SIM0085Sarilumab
CD27SIM0087Varlilumab　Integrin α4β7SIM0024Vedolizumab
CD28SIM0105Theralizumab　LAG-3SIM0015Relatlimab
CD30SIM0073Brentuximab　MesothelinSIM0040Amatuximab
CD326SIM0045Edrecolomab　nectin-4SIM0031Enfortumab
CD37SIM0106Otlertuzumab　NGFSIM0017Tanezumab
CD38SIM0034Daratumumab　PCSK9SIM0095Evolocumab
SIM0092Isatuximab　SIM0096Bococizumab
CD40SIM0072Sotigalimab　PD-1SIM0003Nivolumab
CD79bSIM0060Polatuzumab　SIM0010Pembrolizumab
CEACAM5SIM0039Labetuzumab　SIM0037Cemiplimab
CEACAM6SIM0063Tinurilimab　SIM0009Atezolizumab
CGRPSIM0101Eptinezumab　SIM0038Tislelizumab
CGRPRSIM0103Erenumab　SIM0054Sintilimab
Claudin 18.2SIM0026Zolbetuximab　PD-L1SIM0009Atezolizumab
CLEVER-1SIM0100Bexmarilimab　SIM0021Avelumab
CTLA-4SIM0004Ipilimumab　SIM0027Durvalumab
SIM0046Tremelimumab　RANKLSIM0028Denosumab
CXCL10SIM0076Eldelumab
RSVSIM0088Nirsevimab
EGFRSIM0002Cetuximab
SLAMF7SIM0041Elotuzumab
SIM0050Panitumumab
SOSTSIM0068Romosozumab
FcRnSIM0062Nipocalimab
TIGITSIM0033Tiragolumab
FGF‑23SIM0079Burosumab
TIM-3SIM0043Sabatolimab
FGFR2bSIM0052Bemarituzumab
TNFαSIM0102FABCertolizumab
FOLR1SIM0071Mirvetuximab
SIM0001Adalimumab
GDF15SIM0059Ponsegromab
SIM0006Infliximab
GLP-1SIM0077Dulaglutide
SIM0064Golimumab
SIM0082Semaglutide
TROP-2SIM0051Sacituzumab
GPNMBSIM0066Glembatumumab
TSLPSIM0036Tezepelumab
HER2SIM0005Trastuzumab
VEGFSIM0007Bevacizumab
SIM0019Pertuzumab
VEGFR-2SIM0012Ramucirumab
IFNAR1SIM0022Anifrolumab
VISTASIM0057Onvatilimab
IFNγSIM0074Emapalumab
α4β7SIM0018Natalizumab
IgESIM0016Omalizumab
4-1BBSIM0058Urelumab
IGF-1RSIM0070Teprotumumab



Custom 서비스

Bio X Cell은 연구 요구에 따라 카탈로그 항체를 맞춤 제작할 수 있는 서비스를 제공합니다.

ccecbbfc13931.pngIsotype, Species 변경 및 항체 엔지니어링  
8699703374ec0.pngFc effector 기능 조절
3f03346839a91.pngmg 부터 g 까지 맞춤 대량 생산
56c28e1a15b18.png검출 및 multiplexing을 위한 항체 표지




* 학술 문의: (주)다윈바이오

  Tel. 031-728-3231 / E-mail. dawinbio@dawinbio.com

#BioXCell  #InVivo #항체 #고순도 #Endotoxin #Custom #대량생산 #Biosimilar #InVivoSIM
 #Murine #Antibody #다윈바이오 #DAWINBIO

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