알림
뒤로

Tools[Abcam] Cell and gene therapy solutions

Abcam
조회수 189

fc71b668735f9.jpg

3a0067fa10627.jpg


Cell and gene therapy solutions


세포, 유전자 치료 연구를 앞당기세요! Abcam의 고품질의 분석 kit와 시약을 이용하여, 연구 효율을 극대화할 수 있습니다. 


Immunoassays

분비된 cytokine의 정량부터 viral vector 역가 측정까지, Abcam의 SimpleStep ELISA kit는 90분 이내에 데이터를 제공합니다. 단 한 번의 washing step으로, ELISA의 품질과 성능을 저하시키지 않으면서 실험 과정을 효율적으로 간소화할 수 있습니다. 또한 일부 SimpleStep 제품은 384-well 포맷으로도 제공되어, 실험 규모를 확장할 수 있습니다.

아울러, T cell 활성화를 평가하거나 숙주 세포 단백질 (HCPs; host cell proteins)을 측정할 수 있는 ELISpot kit, 그리고 잔류 HCP를 측정하기 위한 ELISA kit 등 다른 면역분석 제품들도 제공하고 있습니다.


TargetSample typeReactivityDetection rangeCat no.
CCL2Cell culture supernatant, Cerebral Spinal Fluid, Plasma (Citrate, EDTA, Heparin), Serum, UrineHuman4.7 - 300 pg/mLab179886
CCL5Cell culture supernatant, Plasma (Citrate, EDTA, Heparin), SerumHuman0.94 - 60 pg/mLab174446
CD40LCell culture supernatant, Plasma, SerumHuman12.5 - 800 pg/mLab196268
CXCL10/IP-10Cell culture supernatant, Plasma (Citrate, EDTA, Heparin), SerumHuman12.5 - 800 pg/mLab173194
GM-CSFCell culture media, Cell culture supernatant, Plasma (Citrate, EDTA, Heparin), SerumHuman15.625 - 1000 pg/mLab174448
Granzyme BCell culture supernatant, Plasma (Citrate, Heparin), SerumHuman156 - 10000 pg/mLab235635
H1V1 p24Cell culture supernatant, Plasma (Citrate, EDTA, Heparin), SerumHuman immunodeficiency virus15.625 - 1000 pg/mLab320051
IFN betaCell culture supernatant, Plasma (Citrate, EDTA, Heparin), SerumHuman9.38 - 600 pg/mLab278127
IFN gammaCell culture supernatant, Plasma, SerumHuman0.468 - 30 ng/mLab174443
IL-1 betaCell culture supernatant, Plasma (Citrate, EDTA, Heparin), SerumHuman14.06 - 900 pg/mLab214025
IL-1raCell culture extracts, Cell culture supernatant, Milk, Plasma, Saliva, Serum, Tissue Extracts, UrineHuman7.81 - 500 pg/mLab211650
IL-2Cell culture media, Cell culture supernatant, Plasma (EDTA, Heparin), SerumHuman39 - 2500 pg/mLab270883
IL-4Cell culture supernatant, Plasma (Citrate, EDTA, Heparin), SerumHuman6.25 - 400 pg/mLab215089
IL-6Cell culture supernatant, Cerebral Spinal Fluid, Plasma (Citrate, EDTA), SerumHuman7.8 - 500 pg/mLab178013
IL-7Cell culture media, Plasma (Citrate, EDTA), SerumHuman18.8 - 1200 pg/mLab270218
IL-8Cell culture supernatant, Cerebral Spinal Fluid, Plasma (Citrate, EDTA, Heparin), SerumHuman3.91 - 250 pg/mLab214030
IL-10Cell culture supernatant, Plasma (Citrate, EDTA, Heparin), SerumHuman9.4 - 3000 pg/mLab185986
IL-15Cell culture extracts, Cell culture supernatant, Plasma (Citrate, EDTA, Heparin), Serum, Tissue ExtractsHuman3.9 - 250 pg/mLab218266
IL-17aCell culture supernatant, Plasma (Citrate, EDTA, Heparin), SerumHuman3.125 - 200 pg/mLab216167
PD-L1Cell culture supernatant, Cell Lysate, Plasma (Citrate, EDTA, Heparin), Serum, UrineHuman7.81 - 500 pg/mLab277712
TNF alphaCell culture supernatant, Cerebral Spinal Fluid, Plasma (Citrate, EDTA, Heparin), SerumHuman15.63 - 1000 pg/mLab181421
VEGFCell culture extracts, Cell culture supernatant, Cerebral Spinal Fluid, Milk, Plasma (Citrate, EDTA, Heparin),  Saliva, Serum, UrineHuman12.5 - 800 pg/mLab222510


Cell viability / Cell proliferation assays

Abcam에서는 고객의 필요에 맞도록 다양한 size의, 높은 인용도를 가진, 사용이 간편한 cell viability / cell proliferation assay 제품들을 제공합니다. 이러한 assay는 가장 보편적으로 사용되는 flow cytometer, plate reader, 형광 현미경, 그리고 기타 분석 장비를 통해 결과를 측정할 수 있습니다.

무엇부터 시작해야 할 지 고민되시나요? Abcam의 cell viability dye selection guide를 확인해 보세요.


CategoryProduct nameSample typeDetection methodCat no.
Cell proliferataionCFSE - Cell Labeling KitCellsFluorescentab113853
EdU Assay / EdU Staining Proliferation Kit (iFluor 488)Adherent cells, Suspension cellsFluorescentab219801
Cell viabilityCell Counting Kit 8 (WST-8 / CCK8)Adherent cells, Suspension cellsColorimetricab228554
XTT Assay KitAdherent cells, Suspension cellsColorimetricab232856
MTS Assay Kit (Cell Proliferation) (Colorimetric)Adherent cells, Suspension cellsColorimetricab197010
Cell Viability Assay Kit (Fluorometric - Blue Ex 405 nm)Suspension cellsFluorescentab176748
Resazurin Assay Kit (Cell Viability)Adherent cells, Suspension cellsFluorescentab129732
TMRE-Mitochondrial Membrane Potential Assay KitAdherent cells, Suspension cellsFluorescentab113852
CytotoxicityLDH Assay Kit (Cytotoxicity)Adherent cells, Suspension cellsColorimetricab65393
Live and Dead Cell AssayAdherent cells, Suspension cellsFluorescentab115347
Stains dead cellsDRAQ7™CellsFluorescentab109202


Flow cytometry antibodies

Abcam의 매우 민감하고 특이성 높은 recombinant monoclonal antibody 포트폴리오는 CAR-T 세포 치료 연구 및 개발에 활용될 수 있으며, 여기에는 면역 세포 및 종양 세포 집단에 대한 flow cytometry 기반 분석과 조직 표본에 대한 IHC 기반 분석이 포함됩니다. Alexa Fluor®, FITC, PE, APC 등 다양한 라벨이 conjugation된 1차 항체 리스트 중에서 원하시는 제품을 선택하실 수 있습니다. 특정 항체의 라벨링이 필요한 경우, abcam의 carrier-free 항체와 완전히 호환되는, 빠르고 사용이 간편한 Lightning-Link® conjugation kit를 사용하실 수 있습니다.


Marker ofTargetReactivityApplicationCat no.
T cellCD3HumanFlow Cytab86883
CD4Human
Flow Cyt
ab218628
Activated T cellPD1Human
Flow Cyt, ICC/IF, IHC-Fr, IHC-P, WB
ab52587
Pan-leukocyteCD45Human
Flow Cyt
ab123522
Th1 cellCD28Human
Flow Cyt
ab85986
T-bet / Tbx21Human, Mouse, Rat
Flow Cyt, IHC-P, WB
ab307193
Th1 T cell, Killer CD8 T cell, Helper CD4 T cell
IFN GammaHuman
Flow Cyt (Intra), WB
ab267369
Th1 T cell, Killer CD8 T cell
TNF alphaHuman
Flow Cyt (Intra), IP, WB
ab255275
Th1 T cell, Effector memory T cellCD45ROHuman
Flow Cyt, IHC-P, WB
ab23
Th2 T cellCXCR4Human
Flow Cyt (Intra), ICC/IF, IHC-P, WB
ab181020
GATA3Human, Mouse
ChIP, Flow Cyt (Intra), ICC/IF, IHC-P, WB
ab199428
Tim-1Human
Flow Cyt, ICC/IF, WB
ab228973
Th17 T cellIL-6Human
Flow Cyt (Intra), ICC/IF, IP, WB
ab233706
IL-17AHuman
Flow Cyt (Intra), IHC-P, WB
ab189377
Th17 T cell, Helper CD4 T cell
CCR4Human
Flow Cyt, WB
ab315446
Th17 T cell, Tregs
TGF beta Receptor IIHuman
Flow Cyt, ICC/IF
ab270440
Regulatory T cellsCD127Human
Flow Cyt
ab255816
CD152 / CTLA4Human
Flow Cyt
ab216338
FOXP3Human
Flow Cyt
ab187598
IL-2 Receptor alphaHuman, Mouse
Flow Cyt, WB
ab264557
IL-10Human
Flow Cyt, ICC/IF, WB
ab133575
STAT5Human, Mouse, Rat
Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB
ab32043
Naive T cell, Central memory T cell
CCR7Human
Flow Cyt
ab155382
Naive T cell, Central memory T cell, Effector memory T cell
CD62LHuman
Flow Cyt
ab254540
Killer CD8 T cell
CD8Human
Flow Cyt, IHC-P, IP, mIHC
ab245118
EOMES / TBR2Human, Mouse, Rat
Dot, Flow Cyt (Intra), IHC-P, IP, WB
ab315794
Helper CD4 T cellIL-2Human
Flow Cyt (Intra), ICC/IF
ab323413
IL-18Human
Flow Cyt (Intra), IHC-P, WB
ab243091
STAT4 (phospho Y693)Human
Dot, Flow Cyt (Intra), IP, WB
ab313630
Helper CD4 T cell, Regulatory T cell
IL-12Human, Mouse
Flow Cyt (Intra), IHC-P, WB
ab131039
Helper CD4 T cell, Follicular helper T cellCXCR3Human
Flow Cyt
ab259865
Follicular helper T cell
CXCR5Human, Rat
Flow Cyt, ICC/IF, WB
ab254415
Effector memory T cell
CD44Human
Flow Cyt, ICC/IF, IHC-P
ab6124
Central memory T cell
CD62LHuman
Flow Cyt
ab245239


Recombinant proteins

Abcam의 premium bioactive protein은 포유류 세포에서 발현되었으며, endotoxin 수준이 매우낮고, activity, purity 및 identity에 대해 시험을 거칩니다. Abcam의 단백질은 ISO 9001:2015 기준에 따라 제조되며, 배치 간 일관성이 유지되어 가능한 한 가장 신뢰할 수 있는 결과를 제공하도록 설계되었습니다. 모든 단백질은 우수하고 안정적인 생물학적 활성을 보유하고 있어, 세포 배양 배지 또는 기능적 연구에 사용하기에 이상적입니다.


TargetProduct nameExpression systemApplicationCat no.
EGFRecombinant human EGF protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab259398
FGF21Recombinant human FGF21 protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGEab283483
GM-CSFRecombinant human GM-CSF protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab259376
HGFRecombinant human HGF protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab259401
IFN GammaRecombinant Human Interferon gamma protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab259377
IGF1Recombinant human IGF1 protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab270062
IL-1 betaRecombinant human IL-1 beta protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE, sELISA
ab259387
IL-3Recombinant human IL-3 protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab259404
IL-6Recombinant human IL-6 protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE, sELISAab259381
IL-7Recombinant human IL-7 protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab259382
IL-8Recombinant human IL-8 protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab259397
IL-10Recombinant human IL-10 protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab259402
IL-15Recombinant human IL-15 protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE, sELISA
ab259403
IL-22Recombinant human IL-22 protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab280331
MCP1Recombinant human MCP1 protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE, sELISA
ab270081
M-CSFRecombinant human M-CSF protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab259396
SCFRecombinant human SCF protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGEab259391
SDF1Recombinant human SDF1 protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab259416
TNF alphaRecombinant human TNF alpha protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE, sELISA
ab259410
VEGF 165ARecombinant human VEGF 165A protein (Active)
HEK 293 cells
Cell Culture, FuncS, HPLC, Mass Spec, SDS-PAGE
ab259412


Knockout (KO) cell lines

CRISPR-Cas9 기술을 이용해 생성된 Abcam의 유전자 편집 세포주는 세포 유전체 내의 특정 유전자를 정밀하게 불활성화(disrupt) 합니다. 이러한 세포주들은 특이성을 보장하기 위해 광범위한 검증 과정을 거치며, 이를 통해 target 검증, 신호 경로 규명, 질병 연구 및 관련 분야에서 보다 신속한 연구 진전을 가능하게 합니다. 


TargetProduct nameMutation descriptionApplicationCat no.
CD20 (MS4A1)
Human MS4A1 (CD20) knockout Raji cell lineKnockout achieved by CRISPR/Cas9; X = 2 bp deletion; Frameshift: 100%
WBab273871
CD74Human CD74 knockout Raji cell line
Knockout achieved by using CRISPR/Cas9, Homozygous: 13 bp deletion in exon 2
Flow Cyt, Flow Cyt (Intra), WB
ab273378
CD274 (PD-L1)Human CD274 (PD-L1) knockout A549 cell line
Knockout achieved by using CRISPR/Cas9, 1 bp insertion in exon 4 and 2 bp deletion in exon 4 and 7 bp deletion in exon 4
WBab267054
ErbB2 / HER2Human ErbB2 / HER2 knockout MCF7 cell lineKnockout achieved by using CRISPR/Cas9, 143 bp deletion after amino acid Gln90 of the WT ErbB2 / HER2 protein
WBab286260
PRKNHuman PARK2 (Parkin) knockout SH-SY5Y cell lineKnockout achieved by using CRISPR/Cas9, Homozygous: 77 bp deletion in exon 2
WBab280042
TREM2Human TREM2 knockout THP-1 cell line
Knockout achieved by CRISPR/Cas9; X = 1 bp deletion, 2 bp deletion; Frameshift: 97%WBab269489


Cell isolation kits

널리 사용되고 있는 Abcam의 cell isolation kit는 생물학적 시료로부터 분리 대상이 되는 세포의 활성과 생리적 상태를 유지하면서 B cell, T cell 등을 분리할 수 있도록 설계되었습니다.
당사의 T cell 및 B cell isolation kit는 자석이나 컬럼을 사용하지 않아 보다 빠르고 간편한 워크플로우를 제공하며, 그 결과 실험 간 반복 수행에서도 더 높은 분리 수율과 재현성을 확보할 수 있습니다. 


분리 대상 (목적)Product nameReactivitySample typeCat no.
B cellHuman B Cell Isolation KitHumanMononuclear cells
ab322031
Mouse B Cell Isolation Kit
MouseSplenocyteab322026
T cell
Human T Cell Isolation KitHumanMononuclear cells
ab322032
Mouse T Cell Isolation KitMouseSplenocyteab322027
CD4+ T cell
Human CD4+ T Cell Isolation Kit
HumanSplenocyte
ab322033
Mouse CD4+ T Cell Isolation Kit
MouseSplenocyte
ab322028
Mouse Naive CD4+ T Cell Isolation Kit
MouseSplenocyte
ab322029
Polymorphonuclear cells
Whole Blood Polymorphonuclear Cell Isolation Kit
HumanWhole bloodab241001
RBC 제거Human Red Blood Cell Depletion Microbubbles
HumanCellab322034


Exosome 관련 제품

CategoryProduct nameReactivitySample typeCat no.
Exosome capture beadCD9 Exosome Capture Beads
HumanPlasma, Urine, Cell culture media
ab239685
CD63 Exosome Capture Beads
Human
Plasma, Urine, Cell culture media
ab239686
CD81 Exosome Capture Beads
Human
Plasma, Urine, Cell culture media
ab239687
CD326 Exosome Capture Beads
Human
Plasma, Urine, Cell culture media
ab239688
Exosome isolationExosome Isolation and Analysis Kit - Flow Cytometry, Cell culture (CD63 / CD9)
Human
Cell culture mediaab267478
Exosome Isolation and Analysis Kit - Flow Cytometry, Plasma (CD9 / CD81)
Human
Plasma, Serumab267479
Exosome Isolation and Analysis Kit - Flow Cytometry, Urine (CD63 / CD9)
Human
Urineab247480
Exosome antibody panelExosome Panel (Calnexin, CD9, CD63, CD81, Hsp70, TSG101)
Human

ab275018
Exosome ELISA kitOverall Exosome Capture and Quantification Assay Kit
HumanCell culture supernatantab287851
Overall Exosome Capture and Quantification ELISA Assay Kit
HumanPlasmaab285284
Overall Exosome Capture and Quantification Assay Kit (Human Serum, Colorimetric)HumanSerumab287861
Exosome standardLyophilized HT-29 Exosome Standards


ab239690
Lyophilized MCF7 Exosome Standards


ab239691
Lyophilized PC-3 Exosome Standards

ab239689
Lyophilized Exosome Standard (U87 MG)


ab236885
Lyophilized Exosome Standard (Human Plasma)

ab288118
Lyophilized Exosome Standard (100 µg, Human Serum)

ab286846
Lyophilized Exosome Standard (100 µg, Human Urine)


ab286884
B16F10 Fluorescent Exosome Standard


ab288120
Plasma Fluorescent Exosome Standard


ab288123


* 학술 문의: Abcam 공식대리점 (주)다윈바이오

Tel. 031-728-3234, 3237    E-mail. technical@dawinbio.com    카카오톡 플러스친구 ID: abcam

[Abcam] 샘플 희석은 줄이고 결과는 6배 빠르게 - SimpleStep Ignite™ ELISA [Abcam] 재현성 높은 antibody conjugation을 경험해 보세요
목록 글쓰기
TOP